Meet the Experts

Karl Freemyer

Karl Freemyer

Head of Business Development

    How to Develop a Global Value Proposition for Market Access

    Last Updated: October 24th, 2025

    We develop global value propositions by conducting payer research, gap analyses, and targeted literature reviews. We also align with internal teams to create evidence generation plans that optimize market access.

    What Is a Global Value Proposition?

    A global value proposition is a unified narrative of clinical, economic, and real-world benefits tailored for payers across markets. It aims to identify what evidence is needed, what messages resonate, and how to adapt across jurisdictions to support reimbursement and access.

    How Our Technology Delivers Results

    We combine technical expertise with deep healthcare strategy and clinical insights, brought to every project by our team of experts. Our services include:

    • Targeted literature review: We analyzed competitor trials, prior HTA submissions, and analog products.
    • Gap analysis: We evaluated the existing evidence base and identified gaps relative to therapeutic area access requirements.
    • Primary research: We recruited 18 payers across the US, UK, Germany, Spain, Italy, and France to validate the value proposition and evidence plan.

    How Our Practical Agility Keeps Teams Ahead

    Our lean, flexible approach enables seamless teamwork and quick mobilization of resources, ensuring projects move forward efficiently without unnecessary hurdles. Our work includes:

    • Internal stakeholder interviews: Facilitated discussions with client teams across R&D, pricing, medical affairs, and HEOR to align on objectives and evidence needs.
    • Key value message testing: Gathered payer perspectives on critical clinical and economic evidence requirements within a competitive landscape.
    • Payer insights and objection analysis: Collected and synthesized comprehensive feedback on payer perceptions, potential objections, and barriers to market access.
    • Evidence generation plan: Designed a targeted evidence generation strategy to support optimal market access in each relevant country.

    Customer Testimonies

    Why a Strong Global Value Proposition Matters

    It ensures messaging aligns with payer expectations around benefit, risk, and economic value. A strong value proposition exposes evidence gaps early so plans can proactively address them. It aligns internal stakeholders (clinical, HEOR, pricing, market access) around a cohesive narrative. It differentiates the therapy in competitive landscapes, as well as globally.

    A Step Forward in Value Communication

    Our Market Access team helps turn this value proposition into actionable strategies. We guide evidence generation, support payer engagement, and plan for access to achieve optimal reimbursement across global markets. By leveraging our global experience, we ensure strategies are tailored to the unique requirements of each country, maximizing the likelihood of successful market entry.

    Is your therapy’s value clearly resonating with payers across every market?

    Let’s work together to uncover insights, close evidence gaps, and position your therapy for optimal market access.

    Meet our Value Communication Team

    FAQs on Global Value Proposition

    1. When is the right time to develop a global value proposition?
      Clinical, regulatory, and evidence plans can be aligned even in early development stages, before pivotal trials.
    2. Who should be involved?
      Internal stakeholders (R&D, HEOR, medical affairs, pricing) plus external payer or reimbursement experts to validate messaging.
    3. What is the role of gap analysis?
      To pinpoint where evidence is weak or insufficient relative to payer/reimbursement expectations and guide what needs to be generated.
    4. How do payer interviews help?
      They validate how payers perceive value, what clinical or economic evidence they demand, and what objections may arise.
    5. What are typical deliverables?

    Value messaging frameworks, payer feedback reports, country-specific evidence plans, and alignment workshops.

    Meet the Authors

    Karl Freemyer

    Karl Freemyer

    Head of Business Development

      Let's Talk

      Herspiegel is a leading professional services firm helping biotech start-ups and the world’s largest pharmaceutical companies navigate the path from science to brand performance and change patients’ lives. We are committed to using strategic insights from medical to commercial to market access to solve critical problems.