Optimizing Communication Strategies for Stakeholder and Scientific Alignment
Introduction
Our client had a molecule recognized for its efficacy in reducing innate immunogenicity, previously applied in other therapeutic areas. They sought to extend its application to a degenerative neurological disorder, which posed a significant departure from their established therapeutic areas.
The Problem
The client faced significant challenges in advancing their molecule’s clinical development for a degenerative neurological disorder due to limited data and scientific support for their unconventional therapeutic approach. They needed to identify the most efficient and cost-effective strategy to communicate the scientific rationale and advance the program.
Our Solution
- Created a high-level narrative aligning the MOA with the new indication, leveraging data and aspirational statements to guide evidence generation
- A communication strategy was developed, focusing on the evolution of the desired narrative over time pre- and post-data readout
- High ROI activities were identified, which required strong academic KOL engagement and focused congress presentations
- Advisory boards were organized with experts on disease pathophysiology and the relevance of the MOA. We identified critical biomarkers for investigation and publication to bolster the communication strategy
- Key abstracts and posters were prepared for priority regional congresses, offering a cost-effective method to disseminate information to key stakeholders
Value Delivered
- Refined communication strategies through KOL engagement, poster presentations, and feedback
- Successfully aligned strategies with both stakeholder expectations and evolving scientific developments
